Use of platelet-rich fibrin in regenerative dentistry: a systematic review

A study that examines the use of Platelet-Rich Fibrin (PRF) in regenerative dentistry, which is an approach that aims to repair or replace damaged tissues or organs. The study is a systematic review of the literature and it aims to provide an overview of the current state of knowledge about the use of PRF in regenerative dentistry, including the advantages and disadvantages of its use. The study evaluated the literature on the use of PRF in various dental procedures such as socket preservation, sinus augmentation, guided tissue regeneration and periodontal regeneration, implantology and oral and maxillofacial surgery.

The study found that PRF has a beneficial effect on the healing process and tissue regeneration. It has been shown to be effective in promoting bone formation and tissue repair in various dental procedures. PRF has also been found to be a cost-effective alternative to other treatments, as it is easy to prepare and does not require additional cost for processing.

PRF has been found to be a useful tool in socket preservation, which is a procedure that aims to preserve the bony ridge after tooth extraction to prevent bone resorption. It has also been found to be effective in sinus augmentation, which is a procedure that increases the height of the maxillary sinus floor to allow for the placement of dental implants. In guided tissue regeneration, PRF has been found to be effective in promoting the growth of new periodontal tissue, which helps to stabilize teeth and improve the prognosis of periodontal therapy. In implantology, PRF has been found to be useful in promoting bone formation around dental implants, increasing implant stability and improving implant survival.

The study also found that PRF has potential use in oral and maxillofacial surgery, it has been found to be effective in promoting bone formation and wound healing after jaw surgery. Additionally, the study found that PRF is safe for use, with no reported adverse effects.

In conclusion, the study shows that PRF is an effective and cost-effective tool in regenerative dentistry, promoting healing and tissue regeneration in various dental procedures. However, more studies are needed to fully understand its potential applications and to establish guidelines for its use in clinical practice.